May 31, 2016

Family history of heart disease ups cholesterol risk in kids – Times of India

One in three children along with a strong

family history of heart disease
and/or

Type 2 diabetes
may have actually significantly higher levels of risk for cholesterol than kids along with no family history of those conditions, finds a study.

The findings showed that such children had a higher ratio of total cholesterol and were additionally at risk of cardiometabolic markers — chances for having diabetes, heart disease or stroke.

“One-third of the children in our study had a strong family history of CVD and/or diabetes. These children had higher levels of total cholesterol and a higher ratio of total cholesterol to HDL cholesterol than children along with no family history,” said lead researcher Nina Berentzen from National Institute for Public Health and the Environment in the Netherlands.

Children along with elevated levels of these markers were additionally at risk of increased body mass index (BMI) levels, waist circumference and cholesterol, blood stress and blood sugar control.

Most of the associations between family disease history and cardiometabolic markers persisted, even after adjusting for the BMI of the parents and child.

The study is the first to investigate the occurrence of both diseases across two generations of parents and grandparents and relate it to measurable risk factors in children.

However, “even children along with a healthy weight could be at risk for unfavourable levels of cardiometabolic markers if their parents or grandparents had CVD or diabetes,” Berentzen added in the paper published in the journal Diabetologia.

The team included 1,374 children (704 girls and 670 boys) who had both a clinical assessment at age 12 and parental reports on their family history of CVD and diabetes.

Other characteristics used to describe the children taking part in the study were their sex, ethnicity, age, pubertal development, as well as the age, education level and BMI of their parents and grandparents.

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